Obscurin Acts as a Variable Force Resistor

The Bacterial Fimbrial Tip Acts as a Mechanical Force Sensor

There is increasing evidence that the catch bond mechanism, where binding becomes stronger under tensile force, is a common property among non-covalent interactions between biological molecules that are exposed to mechanical force in vivo. Here, by using the multi-protein tip complex of the mannose-binding type 1 fimbriae of Escherichia coli, we show how the entire quaternary structure of the a...

Multi-Channel Force Sensing Resistor Switch

Geometric characterization of series-parallel variable resistor networks

T h e r a n g e o f o p e r a t i n g c o n d i t i o n s f o r a s e r i e s p a r a l l e l n e t w o r k o f v a r i a b l e l i n e a r r e s i s t o r s , v o l t a g e s o u r c e s , a n d c u r r e n t s o u r c e s c a n b e r e p r e s e n t e d a s a c o n v e x p o l y g o n i n a T h e v e n i n o r N o r t o n h a l f p l a n e . F o r a n e t w o r k w i t h n e l e m e n t s o f...

Traction force on a kinetochore at metaphase acts as a linear function of kinetochore fiber length

We are investigating the relation between the force pulling a kinetochore poleward and the length of the corresponding kinetochore fiber. It was recognized by Ostergren in 1950 (Hereditas 36:1-19) that the metaphase position of a chromosome could be achieved by a balance of traction forces were proportional to the distance from kinetochore to pole. For the typical chromosome (i.e., a meiotic bi...

Dosimetry with a diamond operating as a resistor.

A very pure diamond with contacts of graphite has a linear current-voltage characteristic when subjected to irradiation. The resistivity is inversely proportional to the dose rate and the sensitivity is extremely high for gamma- and X-rays and electron beams. It is concluded that diamond resistors are suitable for clinical radiation dosimetry. This conclusion is also based on earlier work in wh...